7536-55-2 Boc-L-Asn-OH

Boc-L-Asn-OH, wanda kuma aka sani da BOC-L-Asparagine, asalin amino acid ne mai mahimmanci tare da aikace-aikace daban-daban.

Da fari dai, Boc-L-Asn-OH ya sami yaɗuwar amfani a cikin nazarin halittu da gano magunguna.Yana aiki azaman maɓalli mai mahimmanci a cikin haɗin peptide, yana ba da damar gina sarƙoƙi na peptide tare da takamaiman ayyukan ilimin halitta.Saboda kaddarorin sinadarai na musamman, Boc-L-Asn-OH na iya amsawa tare da sauran amino acid ko mahadi, wanda ke haifar da samar da sabbin kwayoyi ko kwayoyin halittu masu rai tare da ayyuka daban-daban.

Na biyu, Boc-L-Asn-OH kuma yana da aikace-aikace a cikin fasahar kere-kere da ilimin halittar kwayoyin halitta.Yana iya aiki azaman amino acid mai kare monomer, yana kare ƙungiyoyi masu aiki a cikin wasu amino acid ko sarƙoƙin peptide daga halayen sinadarai maras so yayin haɗuwa ko tsarkakewa.Bugu da ƙari, ana iya amfani da Boc-L-Asn-OH don ƙayyadaddun gyare-gyare a cikin aikin injiniyan furotin, canza tsari da aikin sunadaran.

Bugu da ƙari kuma, dangane da dabarun samarwa, Boc-L-Asn-OH za a iya haɗa shi ta hanyar takamaiman halayen sinadaran.Yawanci, an shirya shi ta amfani da tert-butoxycarbonyl chloride (ko azide) da L-asparagine a matsayin kayan farawa.Halin acylation yana biye da acidification ta amfani da citric acid sannan kuma tsarkakewa ta hanyar recrystallization.Wannan tsari na samarwa yana ba da damar babban shiri na Boc-L-Asn-OH, biyan buƙatun aikace-aikacen sa daban-daban.